Endocrine Abstracts

Differentiated thyroid cancer (DTC) is the most common malignant neoplasm arising from the thyroid parenchymal cells. DTC risk stratification is a multi-stage process based on investigated histopathological features and ultrasound test outcomes combined with biochemical test results. Thus, searching for novel diagnostic indicators useful in cancer risk stratification are still needed. Recent studies revealed that oxidative and epigenetic alterations in DTC represent the signat...

The most effective conventional treatment for differentiated thyroid cancer (DTC) still remains total thyroidectomy with subsequent adjuvant therapy with radioiodine ablation (RAI). In case of unsuccessful RAI treatment, an alternative method is the tyrosine kinase inhibitor therapy. However, its usage is related to many side effects and is not well tolerated by patients. Despite the great progress in the clinical management of patients with DTC, the lack of alternative therap...